diff --git a/scripts/cmake/PythonSetup.cmake b/scripts/cmake/PythonSetup.cmake
index ef6be751483de6a3bb6e6784b3888f0a98e3cccf..95e3fedcc3179416fdd2bb0b3b2ae0f3da3ab592 100644
--- a/scripts/cmake/PythonSetup.cmake
+++ b/scripts/cmake/PythonSetup.cmake
@@ -40,7 +40,7 @@ else()
 endif()
 
 set(_python_componets Interpreter)
-if(OGS_USE_PYTHON)
+if(OGS_USE_PYTHON AND NOT OGS_WHEEL_BUILD)
     list(APPEND _python_componets Development.Embed)
 endif()
 if(OGS_BUILD_PYTHON_MODULE)